90plus纳米粒度仪应用案例
文献名：thesmallheatshockproteincagefrommethanococcusjannaschiiisaversatilenanoscaleplatformforgeneticandchemicalmodification
作者：michellel.flenniken,deboraha.willits,susanbrumfield,markj.young,andtrevordouglas
departmentofmicrobiology,departmentofchemistryandbiochemistry,departmentofplantsciences,centerforbio-inspirednanomaterials,thermalbiologyinstitute,montanastateuniversity,bozeman,montana59717
摘要：naturehasprovideduswitharangeofreactivenanoscaleplatforms,intheformofproteincagearchitecturessuchasviralcapsidsandthecagesofferritin-likeproteins.proteincagearchitectureshaveclearlydemarcatedexterior,interior,andinterfacesurfacesconsistingofpreciselylocatedchemicalfunctionalities.inthepresentwork,wedemonstratethatthesmallheatshockprotein(mjhsp)cagefrommethanococcusjannaschiiisanewandversatilenanoscaleplatformwhoseexteriorandinteriorsurfacesareamenabletobothgeneticandchemicalmodification.wildtypeandgeneticmutantsofthehspcageareshowntoreactwithactivatedfluoresceinmoleculesinasitespecificmanner.inaddition,the12nmhspcageservesasasizeconstrainedreactionvesselfortheoxidativemineralizationofiron,resultingintheformationofmonodispersed9nmironoxidenanoparticles.theseresultsdemonstratetheutilityofthehspcagetoserveasananoscaleplatformforthesynthesisofbothsoft(organic)andhard(inorganic)materials.